Unequivocal total assignment of13C and1H NMR spectra of some pyrido[1,2-a]pyrimidine derivatives by 2D-NMR

Autor:	Musarat Amina, Naresh Kumar Satti, Om Parkash Suri, Basant P. Wakhloo, Krishan Avtar Suri
Rok vydání:	2003
Předmět:	chemistry.chemical_compound Heteronuclear molecule Pyrimidine Stereochemistry Chemistry Proton NMR General Materials Science General Chemistry Carbon-13 NMR Two-dimensional nuclear magnetic resonance spectroscopy Spectral line Heteronuclear single quantum coherence spectroscopy
Zdroj:	Magnetic Resonance in Chemistry. 41:747-749
ISSN:	1097-458X 0749-1581
DOI:	10.1002/mrc.1240
Popis:	We report the total assignments of the 13C and 1H NMR spectra of some 4-methyl-2-oxo-(2H)-pyrido[1,2-a]pyrimidine and 2-methyl-4-oxo-(4H)-pyrido[1,2-a]pyrimidine derivatives. The products were characterized by 1H and 13C NMR and reported data for similar compounds. No comparative data for the two sets of isomeric compounds with respect to 13C and 1H NMR have been reported to date. We made some detailed studies of the 2D NMR spectra of these compounds and observed that assignments made for non-protonated carbon atoms by us and those reported in the literature for similar compounds need correction. The revised assignments were made on the basis of heteronuclear single quantum correlation (HSQC) and heteronuclear multiple bond correlation (HMBC) techniques. Copyright © 2003 John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
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