| Autor: |
Ana Maria Marinho Da Silva, Luana Lenzi, Cláudio Galvão De Castro Junior, Maria Lucia de Martino Lee, Juliana Teixeira Costa, Mecneide Mendes Lins, Ana Luiza Melo Rodrigues, Lisa Lee-Jones, Alayde Vieira Wanderley, Patrick Rezende Godinho, Raul C. Ribeiro, Cinthya Rocha De Carvalho |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
JBMTCT. 2:77-86 |
| ISSN: |
2675-374X |
| DOI: |
10.46765/2675-374x.2020v2n1p77-86 |
| Popis: |
Objective: To describe the outcome of acute myeloid leukemia (AML) among children treated in Brazilian institutions. Methods: A structured online questionnaire was sent to pediatric oncologists affiliated to the Brazilian Society of Pediatric Oncology. The physicians and institutions were unidentified. Results: One hundred and four pediatric oncologists in all Brazilian regions answered the questionnaire. The treatment-related mortality rate was reported to be higher than 30% by 29.8% of the participants. Difficulty in accessing the intensive care unit (ICU) was reported by 54.8%. About 85% had access to cytogenetics, 78% to molecular testing, 94% to the measurement of residual disease by flow cytometry. About 90% of participants reported access to HSCT, but 86% of them had difficulties in providing HSCT timely. About 95% of the respondents indicated the need to create a national treatment protocol, and 89.4% are willing to collaborate with a national study group. Conclusion: Our study demonstrated large gaps in the treatment of pediatric AML in Brazil. To improve outcome, a national protocol will have to consider the regional differences and adapt the management according to the local resources. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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