Evaluating the effectiveness of pneumococcal vaccines against hospitalization and intensive care unit admission in adults
Autor: | Dina Elgaily, Zainab Albu-Mahmood, Ahmed El-Bardissy, Hani Abdelaziz, Rana Moustafa Al-Adawi, Ahmed Atef Shible |
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Rok vydání: | 2019 |
Předmět: |
COPD
medicine.medical_specialty business.industry Economics Econometrics and Finance (miscellaneous) Retrospective cohort study medicine.disease Intensive care unit law.invention Vaccination Pneumonia Pneumococcal vaccine law Diabetes mellitus Emergency medicine medicine business Pharmacology Toxicology and Pharmaceutics (miscellaneous) Asthma |
Zdroj: | Journal of Pharmaceutical Health Services Research. 10:427-431 |
ISSN: | 1759-8893 1759-8885 |
Popis: | Objective: To evaluate the efficacy of pneumococcal vaccines concerning hospital or intensive care unit (ICU) admissions due to pneumonia after vaccination. Setting: Inpatient and ICUs at Hamad General Hospital. Methods: The retrospective study included adults who were vaccinated between June 2012 and June 2013. Patient records were reviewed for hospital or ICU admissions due to pneumonia 2 years before and after vaccination. Main outcomes measures: The primary outcome was to compare the rates of hospital and ICU admissions for pneumonia 2 years before and after vaccination. The secondary outcome was to evaluate the efficacy of pneumococcal vaccines against different comorbidities. Key findings: One hundred sixty-one patients were included with a dominant age group of 64–85 (52%) years old. Comorbidities reported were hypertension (HTN), diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD) and asthma. The rate of hospital admission due to pneumonia was significantly reduced within 2 years after vaccination, 71–39% (P 0.72). In diabetic, hypertensive and COPD/Asthma patients, there was a statistically significant reduction in hospitalization. Although there was a reduction in ICU admission for both commodities, the results did not achieve statistical significance. Conclusion: Adults who received pneumococcal vaccines experienced reduced rates of hospital versus ICU admissions due to pneumonia infection. |
Databáze: | OpenAIRE |
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