Stereoelectronic requirements for a new class of asymmetric ketone reduction catalysts containing an NPO structural unit
| Autor: | Martin Wills, John R. Studley, Heather Tye, N. Paul King, Barry Burns |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
chemistry.chemical_classification
Reaction mechanism Ketone Chemistry Organic Chemistry Enantioselective synthesis Borane Combinatorial chemistry Catalysis Inorganic Chemistry Reduction (complexity) chemistry.chemical_compound Chemical reduction Organic chemistry Physical and Theoretical Chemistry Structural unit |
| Zdroj: | Tetrahedron: Asymmetry. 5:801-804 |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/s0957-4166(00)86231-x |
| Popis: | A number of new catalysts for the asymmetric reductions of ketones by borane are described. The highest accelerations are achieved by catalysts in which the phosphinamide (R 2 NPO) unit can adopt a planar geometry. This observation has provided an insight into the mechanism of catalysis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|