Combination laser therapy for epiretinal membrane: a physico-mathematical model
| Autor: | K. P. Takhchidi, G I Zheltov, T. A. Kasminina, E. P. Tebina, G. F. Kachalina |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
genetic structures medicine.diagnostic_test General Medicine medicine.disease 01 natural sciences 010309 optics 03 medical and health sciences 0302 clinical medicine Optical coherence tomography Laser therapy 0103 physical sciences 030221 ophthalmology & optometry medicine sense organs Epiretinal membrane Biomedical engineering |
| Zdroj: | TARGETED ONCOTHERAPY. :96-102 |
| ISSN: | 2542-1204 2500-1094 |
| DOI: | 10.24075/brsmu.2019.032 |
| Popis: | An epiretinal membrane (ERM) is a product of abnormal cell proliferation on the inner surface of the retina and at the vitreomacular interface. Laser therapy is an interesting modality for treating pathologies of the vitreomacular interface. The wise choice of laser settings (wavelength, exposure time, power) minimizes damage to the retina and ensures a good therapeutic effect. This could be a serious impetus to the development and refinement of laser technologies for treating ERM. This work investigates the biophysical response of structural retinal components, including the dynamics of temperatures and acoustic oscillations, protein denaturation, and stimulation of tissue regeneration, to a quasi-cw laser beam and a subsequent series of laser micropulses. The manuscript also analyzes the mechanisms underlying the therapeutic effect of the proposed laser therapy in patients with ERM. |
| Databáze: | OpenAIRE |
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