Lymphocyte Blastogenesis Induced by Potassium Chloride Extracts of Allogeneic Breast Carcinoma and Lymphoid Cells2

Autor:	G. B. Cannon, J. S. Silva, J. L. McCoy, C. M. Leonard, Jack H. Dean, Ronald B. Herberman, M. Middleton
Rok vydání:	1975
Předmět:	Cancer Research business.industry Lymphocyte Potassium Cancer chemistry.chemical_element medicine.disease Lymphocyte blastogenesis medicine.anatomical_structure Oncology Antigen chemistry Immunology Lymphocyte activation Medicine business Breast carcinoma Normal breast
Zdroj:	JNCI: Journal of the National Cancer Institute. 54:1295-1298
ISSN:	1460-2105 0027-8874
DOI:	10.1093/jnci/54.6.1295
Popis:	Lymphocytes from cancer patients and normal individuals demonstrated blastogenesis with allogeneic potassium chloride (3 M KCl) extracts of breast carcinoma cells. Normal individuals reacted with a greater frequency and stronger blastogenic responses to tumor extracts than did breast carcinoma patients; allogeneic extracts may have elicited recognition of normal alloantigens rather than tumor-associated antigens. Normal individuals also responded to 3 M KCl extracts of allogeneic pooled normal leukocytes, normal breast tissue, and other cancers, but did not react to extracts of autologous leukocytes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ee0af9db249fd610cc72ce23e214a819 https://doi.org/10.1093/jnci/54.6.1295 Zobrazit plný text záznamu