Prothrombin Estimation: A Procedure and Clinical Interpretations
Autor: | Shepard Shapiro, Harold A. Campbell, Benjamin Sherwin, Milton H. Redish |
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Rok vydání: | 1942 |
Předmět: |
Vitamin
Prothrombin.activity Prothrombin time medicine.medical_specialty medicine.diagnostic_test business.industry Prothrombin level medicine.disease General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Endocrinology chemistry Hyperprothrombinemia hemic and lymphatic diseases Internal medicine Medicine business Hypoprothrombinemia circulatory and respiratory physiology |
Zdroj: | Experimental Biology and Medicine. 50:85-89 |
ISSN: | 1535-3699 1535-3702 |
DOI: | 10.3181/00379727-50-13705 |
Popis: | SummaryThe difference between prothrombin times of whole and diluted plasma is a more reliable guide to prothrombin activity of the blood than is the prothrombin time of either alone. The difference has been found to be fairly constant in normal individuals. When prolonged, it indicates hypoprothrombinemia. When reduced, it may signify hyperprothrombinemia or an excess of anticoagulants in the blood. The procedure recommended is well suited for following the therapeutic effects of agents which influence the prothrombin level (or activity) such as dicumarol or vitamin K. |
Databáze: | OpenAIRE |
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