SERUM ANDROGENS, SEX HORMONE BINDING GLOBULIN AND BONE AGE IN JUVENILE DIABETICS
Autor: | P H Rayner, S K Jivani, G Holder, B T Rudd |
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Rok vydání: | 1975 |
Předmět: |
medicine.medical_specialty
biology medicine.drug_class business.industry Radioimmunoassay Bone age Androgen medicine.disease Sex hormone-binding globulin Endocrinology Internal medicine Diabetes mellitus Pediatrics Perinatology and Child Health Bone maturation medicine biology.protein Juvenile business Testosterone |
Zdroj: | Pediatric Research. 9:673-673 |
ISSN: | 1530-0447 0031-3998 |
DOI: | 10.1203/00006450-197508000-00055 |
Popis: | In males with diabetes mellitus presenting in childhood, puberty may be delayed. Serum androgens (SA), chronological age (CA), bone maturation (BA) and sex hormone binding globulin (SHBG) capacity of sera were recorded in 58 male juvenile diabetics aged 5.2/12 – 19.3/12. Tanner pubertal rating and SHBG capacities were assessed in all. SA (predominantly testosterone) were measured in 57 by radioimmunoassay and BA were obtained in 46 patients. Taking all the patients together, statistically significant correlations were demonstrable between the following parameters:- CA:SA r= 0.75 p = < .001, BA:SA r=0.72 p < .001 (exponential regression), SHBG:SA r= (−)0.36 p = |
Databáze: | OpenAIRE |
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