SERUM ANDROGENS, SEX HORMONE BINDING GLOBULIN AND BONE AGE IN JUVENILE DIABETICS

Autor: P H Rayner, S K Jivani, G Holder, B T Rudd
Rok vydání: 1975
Předmět:
Zdroj: Pediatric Research. 9:673-673
ISSN: 1530-0447
0031-3998
DOI: 10.1203/00006450-197508000-00055
Popis: In males with diabetes mellitus presenting in childhood, puberty may be delayed. Serum androgens (SA), chronological age (CA), bone maturation (BA) and sex hormone binding globulin (SHBG) capacity of sera were recorded in 58 male juvenile diabetics aged 5.2/12 – 19.3/12. Tanner pubertal rating and SHBG capacities were assessed in all. SA (predominantly testosterone) were measured in 57 by radioimmunoassay and BA were obtained in 46 patients. Taking all the patients together, statistically significant correlations were demonstrable between the following parameters:- CA:SA r= 0.75 p = < .001, BA:SA r=0.72 p < .001 (exponential regression), SHBG:SA r= (−)0.36 p =
Databáze: OpenAIRE