Impact of gold-decorated tantalum oxide (TaOx-Au) nano-probes for low energy cancer diagnostic agent
| Autor: | B. Swathi Lakshmi, N. Ashwin Kumar, M. Hema Brindha, Ganapathy Krishnamurthi |
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| Rok vydání: | 2022 |
| Předmět: |
inorganic chemicals
Materials science Mechanical Engineering technology industry and agriculture Nanoparticle Nanotechnology respiratory system Condensed Matter Physics Imaging agent Low energy Mechanics of Materials Diagnostic agent mental disorders Nano General Materials Science Tantalum oxide Molecular imaging health care economics and organizations |
| Zdroj: | Materials Letters. 308:131234 |
| ISSN: | 0167-577X |
| Popis: | We report the synthesis and characterization of Tantalum Oxide nanoparticles (TaOx NPs) and the Gold (Au) decorated Tantalum Oxide (TaOx-Au NPs), an efficient imaging agent for cancer diagnostics. Using an X-ray Micro-CT system, we have compared the X-ray attenuation properties of TaOx and TaOx-Au NPs. We specifically test these nanoparticles by varying the tube current and voltage for low energy X-ray molecular imaging applications. At 100 keV, increased X-ray attenuation was attributed to TaOx-Au NPs compared to TaOx NPs. Our study demonstrates the use of TaOx-Au NPs as suitable for molecular imaging in small animals using low-energy X-rays for cancer diagnosis. |
| Databáze: | OpenAIRE |
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