Experimental Model of Sudden Cardiac Death Morphogenesis in Hyperandrogenaemia

Autor: V. V. Filatov, Zh. R. Omarova, M. V. Mnikhovich, L. V. Kakturskiy
Rok vydání: 2016
Předmět:
Zdroj: Journal of Anatomy and Histopathology. 5:90-96
ISSN: 2225-7357
Popis: The paper summarizes the literature data on the effect of testosterone and its synthetic derivatives on athletes. Biosynthetic pathways and metabolism of testosterone, testosterone signaling pathway, its main biological effects have been characterized. The main attention is paid to the problems of hypo- and hyperandrogenaemia as the two extreme manifestations of deviation from the physiological level of testosterone in the blood of men. Therefore prospects for further studies were identified: hyperandrogenism influence on the heart muscle in athletes and in men who use natural or synthetic analogs of testosterone as a means of increasing physical endurance and activity.
Databáze: OpenAIRE