Benzyl Alcohol in Neuromuscular Blocking Agents

Autor:	ANDRE L. VAN DER HAL, HUGH M. MACDONALD, LAURENCE SHAW, SUKSHMA SREEPATHI, SCOTT A. BEASLEY
Rok vydání:	1987
Předmět:	Pediatrics Perinatology and Child Health
Zdroj:	Pediatrics. 79:841-842
ISSN:	1098-4275 0031-4005
DOI:	10.1542/peds.79.5.841a
Popis:	To the Editor.— Recent letters to the Editors1,2 suggested discontinuation of clinical trials with doxapram for apnea of prematurity, because the preparation contains the preservative benzyl alcohol, implicated as the cause for the gasping syndrome at doses of 94 to 245 mg/kg/d.3 After we reexamined our standard arsenal of drugs used in the neonatal intensive care unit, we found an additional class of drugs containing benzyl alcohol: neuromuscular blocking agents. Pancuronium bromide (Pavulon, [Organon]) is prepared in 1-mg/mL vials containing 1% (10 mg/mL) benzyl alcohol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::edd365a02886d5c5ba3203c568e941b2 https://doi.org/10.1542/peds.79.5.841a Zobrazit plný text záznamu