Preliminary study into the impact of immunotherapy on patterns of care and healthcare service utilization in stage IV non-small cell lung cancer in a tertiary hospital setting

Autor:	Xiao Yue Guo, Jasotha Sanmugarajah, Ben Gunawan
Rok vydání:	2019
Předmět:	Oncology Patterns of care Cancer Research medicine.medical_specialty Hospital setting business.industry medicine.medical_treatment Cancer Immunotherapy medicine.disease Stage IV non-small cell lung cancer Clinical evidence Internal medicine medicine Non small cell Healthcare service business
Zdroj:	Journal of Clinical Oncology. 37:92-92
ISSN:	1527-7755 0732-183X
Popis:	92 Background: The advent of immunotherapy for Non-Small Cell Lung Cancer (NSCLC) has dramatically altered cancer care. There is increasing clinical evidence to support immunotherapy improving disease-free progression and survivorship. However, there is limited data on how this impacts healthcare in terms of service utilization. Methods: We conducted a retrospective study on patients newly diagnosed with Stage IV NSCLC at a tertiary referral hospital with a large catchment area in Australia. Data was collected for the years 2013 (pre-immunotherapy) and 2016 (immunotherapy in use) to investigate the impact of immunotherapy on treatment patterns, survivorship and healthcare service utilisation. A total of 62 patients were included in the study with equal numbers in both cohorts. Results: Preliminary analysis indicates that since the introduction of immunotherapy in NSCLC treatment protocols, there has been a trend towards improved survivorship. There was a 19% increase in the number of patients surviving to 12 months in the 2016 cohort compared with 2013 cohort patients. Median survival was 6 months and 8 months for 2013 and 2016 cohorts respectively. There was a significantly greater burden of visits to outpatient clinics and treatment day units in the 2016 cohort. We also found fewer Emergency Department presentations and hospital admissions in the 2016 cohort compared with their 2013 counterparts. Conclusions: In conclusion, our study demonstrates increasing healthcare utilisation in ambulatory cancer services with decreased Emergency presentations and hospital admissions following the introduction of immunotherapy for patients with advanced NSCLC. Although this preliminary study suggested important trends, our sample size was small and these effects need to be confirmed in a larger cohort. [Table: see text]
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::edc41ddb1013fb5f1fc3bd94a657438b https://doi.org/10.1200/jco.2019.37.8_suppl.92 Zobrazit plný text záznamu