Association of adherence to long-acting inhaler use for initial treatment of chronic obstructive pulmonary disease and acute exacerbation: A retrospective cohort study

Autor: Hee-Sook Suh, Min-Seok Chang, Iseul Yu, Sunmin Park, Ji-Ho Lee, Seok Jeong Lee, Won-Yeon Lee, Suk Joong Yong, Sang-Ha Kim
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1825891/v1
Popis: Background This study aimed to determine the effect of long-acting inhaler medication use adherence on acute exacerbations in treatment-naïve patients with chronic obstructive pulmonary disease (COPD) from healthcare claim data. Methods Using the Korean Health Insurance Review and Assessment Service database from July 2015 to December 2016, patients with COPD aged ≥ 40 who had started using long-acting inhalers were enrolled and observed for 6 months. Patients who were prescribed long-acting inhalers and had been hospitalized or visited emergency department (ED) for COPD 6 months before the first prescription were excluded. Medication adherence was indirectly measured by the medication possession ratio (MPR) based on the adherence (MPR ≥ 80%) and non-adherence (MPR
Databáze: OpenAIRE