577 Hemodynamic Effects of a Catheter-Deployed Intra-Aortic Micro-Axial Entrainment Pump in a Mock Circulatory System
| Autor: | Michael P. Cuchiara, Jason J. Heuring, B.A. Hertzog, F. Raissi Shabari, Reynolds M. Delgado, Joggy George |
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| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
Heart transplantation Transplantation Cardiac output medicine.medical_specialty business.industry medicine.medical_treatment Hemodynamics medicine.disease medicine.anatomical_structure Heart failure medicine.artery Internal medicine Pulmonary artery Circulatory system Vascular resistance medicine Ventricular pressure Cardiology Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Journal of Heart and Lung Transplantation. 31:S200 |
| ISSN: | 1053-2498 |
| Popis: | their follow-up rightheart pressure measured, including cardiac output determination by termodilution, at 32 to 141 days after LVAD implantation. 7pts had additional follow-up rightheart catheterization a few weeks after successful OHTX. Results: Follow-up hemodynamic assessment after LVAD implantation revealed a significant decrease in pulmonary vessel bed pressures compared with pre-implant values. Mean pulmonary artery pressure (MPAP) decreased from an average pre-implant value of 51 7 mmHg to 21 5 mmHg, a decrease in the mean transpulmonary gradient from 20 6 mmHg 10 4 mmHg and an increase in mean cardiac output from 3,2 0,7 to 4,1 1,0 l/min resulted in a decrease in calculated mean pulmonary vascular resistance from 6,3 1,3 Wood units to an acceptable 2,6 0,8 Wood units (all: p 0,001), making it possible to put and/or put again these patients on the waiting list for OHTX. After a few months (between days 127 and 542) of left ventricular pressure unloading, 7 patients (58%) had successful heart transplantation with 100% survival currently at 197 to 995 days posttransplant (mean duration of 500 days). Conclusions: HeartMate II LVAD implantation is an effective therapeutic option for management of severe PH in chronic heart failure patients, making them eligible for inclusion into the waiting list for OHTX. |
| Databáze: | OpenAIRE |
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