Spontaneous Tumors in p53-Deficient Mice
Autor: | Ken-ichi Yoshijima, Masaaki Okada, Tomoko Imaeda, Takashi Nishio, Tsuneo Koike, Akihiro Shinoda, Yutaka Tanikawa, Hitoshi Kimura |
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Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Journal of Toxicologic Pathology. 10:239-242 |
ISSN: | 1881-915X 0914-9198 |
Popis: | The p53-deficient mice (Riken mice) were examined for tumors occurring spontaneously histopathologically and hematologically. Histopathologically, 87% of the males with tumors and 86% of the females with tumors had malignant lymphomas or lymphatic hyperplasia. It must be safe to say that more marked tendency to have spontaneous malignant lymphomas is seen in the p53-deficient mouse. |
Databáze: | OpenAIRE |
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