Spontaneous Tumors in p53-Deficient Mice

Autor: Ken-ichi Yoshijima, Masaaki Okada, Tomoko Imaeda, Takashi Nishio, Tsuneo Koike, Akihiro Shinoda, Yutaka Tanikawa, Hitoshi Kimura
Rok vydání: 1997
Předmět:
Zdroj: Journal of Toxicologic Pathology. 10:239-242
ISSN: 1881-915X
0914-9198
Popis: The p53-deficient mice (Riken mice) were examined for tumors occurring spontaneously histopathologically and hematologically. Histopathologically, 87% of the males with tumors and 86% of the females with tumors had malignant lymphomas or lymphatic hyperplasia. It must be safe to say that more marked tendency to have spontaneous malignant lymphomas is seen in the p53-deficient mouse.
Databáze: OpenAIRE