DVT exclusion in symptomatic outpatients: use of a rapid D-dimer immunofiltration assay and comparison with three enzyme immuno assays

Autor:	I. Chiappino, F. Pautasso, S. Valpreda, C. Rabbia, A. Giorgianni, A. Pannocchia, Mario Bazzan, E. Aluffi, D. Roglia, G. Lanfranco
Rok vydání:	1996
Předmět:	chemistry.chemical_classification medicine.medical_specialty business.industry Hematology Predictive value Gastroenterology Molecular biology Immuno assay Enzyme chemistry Internal medicine D-dimer medicine cardiovascular diseases business
Zdroj:	Fibrinolysis. 10:117-119
ISSN:	0268-9499
DOI:	10.1016/s0268-9499(96)80064-6
Popis:	Summary Many authors have shown that plasma measurement of the degradation products of cross-linked fibrin, D-dimer, may be able to identify patients without DVT. Enzyme Immuno assay (EIA) have shown the best performance characteristics with a sensitivity and a negative predictive value around 100%. These tests are time-consuming and therefor non applicable in the rapid exclusion of DVT. The immunofiltration test we have studied showed a good correlation with three EIA tests of known performance characteristics. This test has a sensitivity and predictive negative value comparable to EIA but is more rapid and thus suitable as a rapid exclusion test for DVT.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ed444be04a241791061fe5e8c3280055 https://doi.org/10.1016/s0268-9499(96)80064-6 Zobrazit plný text záznamu Full Text from ScienceDirect