Benign Odontogenic Tumors: Origins, Immunophenotypic Features, and Genetic Alterations
| Autor: | Qilin Xu, Lee Carrasco, Anh D. Le, Chunmiao Jiang, Qunzhou Zhang, Steven Wang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Mesenchymal stem cell Soft tissue Histology 030206 dentistry Biology Gene mutation Phenotype Odontogenic Pathogenesis stomatognathic diseases 03 medical and health sciences 0302 clinical medicine stomatognathic system Immunology and Microbiology (miscellaneous) 030220 oncology & carcinogenesis medicine Oral and maxillofacial surgery Surgery Oral Surgery |
| Zdroj: | Current Oral Health Reports. 3:93-101 |
| ISSN: | 2196-3002 |
| DOI: | 10.1007/s40496-016-0087-x |
| Popis: | Odontogenic tumors are lesions derived from the epithelial and/or mesenchymal elements of the tooth-forming apparatus and are therefore found within the jaw bone or soft tissue overlying teeth. These tooth development-associated tumors are generally benign, but several odontogenic tumors are capable of aggressive growth and locally invasive behavior with a high rate of recurrence. Benign odontogenic tumors can pose diagnostic challenges because of overlapping histology, a lack of distinct phenotypic and molecular features, and an unclear pathogenesis of the tumors. In this article, we will review the possible origins, immunophenotypic features, and genetic alterations of the common benign odontogenic tumors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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