| Autor: |
V. M. Bazas, N. L. Cheremshenko, O. O. Krutz, I. M. Voeykova, Н. V. Didenko, H. S. Lisovenko, H. P. Potebnya |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Medical and Clinical Chemistry. 17 |
| ISSN: |
2410-681X |
| Popis: |
Blood serum of BALB/c mice immunized with chicken embryonic proteins (CEP) in combination with adjuvantsof microbial origin has been investigated by methods of enzyme immunoassay and immunoblotting. The analysisof accumulation of antibodies to CE P and the study of antibody-dependent cytotoxicity of lymphocytes against thetumor cells of the model suggest that the use of adjuvants of microbial origin, such as protein-containing metabolitesof culture fluid (18.5 and 70 kDa) and lipid fraction of В. subtilis B-7025 cells; S. aureus cell-wall peptidoglycan,contributes to credible strengthening of immune response to fetal antigens. The results of the study are the basisfor creating xenogenic cancer vaccine. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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