| Popis: |
Dioxin a persistent organic pollutants have common molecular form as 2,3,7,8-tetrachlorodibenzo-para-dioxin. There are various natural and anthropogenic sources of dioxin into the environment, which leads to the transfer of this compound into the environment. The major contributor is environment pollution, incarnation and on basis of reports it has been established that major proportions from these sources are deposited onto the atmosphere. From atmosphere it further gets transferred to the food chain and finally gets accumulated in human. Due to the hydrophobic and lipophilic nature they have the property to bioaccumulate in living organisms and cause several health impacts. They react with aryl hydrocarbon (Ah) receptor in the cell and commence a cascade of biochemical reactions which leads to toxicity. This chapter focuses on bioaccumulation of dioxin, routes of transfer of dioxin into organisms its mode of action and harmful impacts. |
