Chemical composition and cytotoxic activity of the leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica

Autor:	Debra M. Moriarity, Ramona A. Cole, William N. Setzer, Anita Bansal, William A. Haber
Rok vydání:	2007
Předmět:	Human tumor Horticulture law Botany Pharmacology toxicology Molecular Medicine Cytotoxic T cell Biology Chemical composition Essential oil law.invention
Zdroj:	Journal of Natural Medicines. 61:414-417
ISSN:	1861-0293 1340-3443
Popis:	The leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica, has been obtained by hydrodistillation and analyzed by GC–MS. The principal constituents of E. zuchowskiae leaf oil were α-pinene (28.3%), β-caryophyllene (13.2%), α-humulene (13.1%), and α-copaene (8.1%). The leaf essential oil of E. zuchowskiae showed pronounced in-vitro cytotoxic activity against MCF-7, MDA-MB-468, and UACC-257 human tumor cell lines. The major components showed cytotoxic activities comparable to doxorubicin (LC50 14–70 μg/ml).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ed297a9dfad1759ba8ca8e16ea8f1f6e https://doi.org/10.1007/s11418-007-0155-6 Zobrazit plný text záznamu Full text from SpringerLink