Synthesis of novel monobactams bearing an (R)-1-hydroxyethyl group and an (S)-1-carbamoyloxyethyl group at the C3,4-positions

Autor:	S. Terashima, Yoshio Ito, Kikoh Obi
Rok vydání:	1990
Předmět:	chemistry.chemical_compound Chemistry Stereochemistry Group (periodic table) Drug Discovery medicine Lactam Monobactam General Chemistry General Medicine Monobactams Antibacterial activity medicine.drug
Zdroj:	Chemical and Pharmaceutical Bulletin. 38:917-924
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.38.917
Popis:	Various structural types of monobactams bearing an (R)-1-hydroxyethyl and an (S)-1-carbamoyloxyethyl group at the C 3,4 -positions, respectively, could be synthesized from (3S,4S)-4-[(S)-1-benzyloxyethyl]-3-[(R)-1-hydroxyethyl]-2-azetidinone. These synthetic studies explored several novel methods applicable to construct substituted carbamoyloxy groups
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ed1334ef21fb8ee51c52c68407b04e54 https://doi.org/10.1248/cpb.38.917 Zobrazit plný text záznamu