Right ventricular assistance for experimental right ventricular dysfunction

Autor: Jett Gk, Robert E. Applebaum, Richard E. Clark
Rok vydání: 1986
Předmět:
Zdroj: The Journal of Thoracic and Cardiovascular Surgery. 92:272-278
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)35908-2
Popis: Right ventricular dysfunction frequently occurs in patients undergoing correction of congenital cardiac defects, as well as in other clinical settings. The purpose of the present study was to surgically induce right ventricular dysfunction and then provide circulatory support with a right ventricular assist device. Right ventricular hypertrophy was created in 13 neonatal lambs by pulmonary artery banding. Right ventricular dysfunction was produced in all animals by performing a right ventriculotomy with the animal supported by cardiopulmonary bypass. In four unassisted animals the circulation failed after separation from bypass. Seven experimental animals underwent the insertion of a pneumatically activated ventricular assist device between the proximal pulmonary artery and the right ventricular apex. Periods with the right ventricular assist device on and off in each animal were compared. The right ventricular assist device increased cardiac output from 0.72 ± 0.15 to 2.24 ± 0.23 L/min (p
Databáze: OpenAIRE