A Case Report of Ivermectin-Induced Prolonged Liver Dysfunction in an Elderly Patient with Scabies

Autor: Tosifusa Toda, Mikako Hirota, Hiraku Morisawa, Satoru Mineshita
Rok vydání: 2011
Předmět:
Zdroj: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 42:341-343
ISSN: 1882-8272
0388-1601
DOI: 10.3999/jscpt.42.341
Popis: Among 30 elderly patients who received ivermectin for the treatment of scabies, we observed a case of possible ivermectin-induced liver dysfunction in an 85 year-old patient. He developed liver dysfunction after the second dose of the drug. While elevated serum ALT and AST subsided to normal levels 2 months after discontinuation of the drug, increased serum ALP and γ-GPT persisted. Ivermectin was effective in all patients for the eradication of scabies.
Databáze: OpenAIRE