Haemoglobin response to intravenous iron in non-dialysis patients with chronic kidney disease and diabetes
| Autor: | Andrew C Burden, Liz Cropper, Senyo Tagboto, Samiul A. Mostafa |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Adult patients business.industry Transferrin saturation Endocrinology Diabetes and Metabolism Intravenous iron medicine.disease Dialysis patients Iron sucrose Gastroenterology Endocrinology Diabetes mellitus Internal medicine Internal Medicine medicine Cardiology and Cardiovascular Medicine Prospective cohort study business Kidney disease medicine.drug |
| Zdroj: | The British Journal of Diabetes & Vascular Disease. 9:126-128 |
| ISSN: | 1753-4305 1474-6514 |
| DOI: | 10.1177/1474651409105381 |
| Popis: | Aims. Our aim is to compare the response of people with or without diabetes to intravenous iron and to evaluate the efficacy of this therapy in improving haemoglobin (Hb) levels in non-dialysis patients according to chronic kidney disease (CKD) stage. Method. This was a prospective study of 100 consecutive adult patients referred to the renal anaemia service for intravenous iron. Patients with other causes of anaemia or receiving erythropoietin therapy were excluded. Patients were given weekly intravenous doses of 200 mg iron sucrose for 4 weeks and monitored at weeks-1 and 5. Data, including diabetic/CKD status, were collated from patient records. Results. Pre-treatment Hb was similar in people with and without diabetes and treatment significantly increased Hb levels (0.5 g/dL, p Conclusion. CKD patients with or without diabetes have similar iron status and Hb response to intravenous iron therapy. Patients with CKD stage 5 respond less well to intravenous iron than patients with CKD stages 3 or 4, despite having similar baseline iron status. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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