Synthesis of Tetracyclic Molecules Containing Medium-Sized Heterocycles: Scope Expansion of Cascade Nicholas and Pauson–Khand Methodology

Autor:	Teppei Sato, Kyosuke Kaneda, Ayaka Fujii, Syuji Ishikawa, Tatsuya Okazaki, Fuma Kamada, Ryoki Nogiwa, Nozomi Akimura, Syota Yamamoto
Rok vydání:	2016
Předmět:	chemistry.chemical_classification Scope (project management) 010405 organic chemistry Pauson–Khand reaction Organic Chemistry Nicholas reaction Alkyne 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences chemistry Cascade Molecule Organic chemistry
Zdroj:	Synthesis. 48:3931-3940
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0035-1562780
Popis:	Unique tetracyclic molecules containing heteroatom-embedded, medium-sized rings were synthesized by employing cascade Nicholas and Pauson–Khand cyclization reactions. We successfully established a divergent synthetic route for quick access to unprecedented multi-ring systems via an alkyne cobalt complex, and an expanded substrate scope for this methodology was realized.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eced7ef230f02463ff9006a6b584f1e0 https://doi.org/10.1055/s-0035-1562780 Zobrazit plný text záznamu