Cutaneous Angiomyolipoma of the Nose
| Autor: | Taiwo Olufemi Solaja, M. A. Akinola, Olalekan Abisola Ajayi, Adekunle Moses Adetayo, Oluwapelumi O. Olusoga-Peters |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Case Reports in Clinical Medicine. :368-375 |
| ISSN: | 2325-7083 2325-7075 |
| Popis: | Angiomyolipomas (AML) are benign mesenchymal tumours. It is commonly seen in the kidney. Extra-renal sites of AML are uncommon though it can occur in any part of the body. Reports of cutaneous AML are rare in the literature. We present a case of an 11-year-old female with a polypoidal swelling on the nose that was noticed a few weeks after birth, which progressively increased in size till it was causing nasal blockage. This cutaneous lesion is different from a renal angiomyolipoma because it lacks features of tuberous sclerosis, non-invasive, absence of epithelioid cells and negative HMB-45 staining. Histopathology shows a mixture of blood vessels, mature adipocytes and smooth muscle. These unique features distinguish this lesion from other possible differentials such as angiomyoma and myolipoma. Histopathology and immunohistochemistry confirm the swelling as angiomyolipoma of the nose. We concluded that histopathology and immunohistochemistry are important diagnostic tools for cutaneous AML irrespective of gender, age of onset and site of lesion. |
| Databáze: | OpenAIRE |
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