Biomarker bei infektiösen und nicht infektiösen Lungenerkrankungen außer Malignome

Autor:	V. Wiechmann, U. R. Jürgens, A. Gillissen
Rok vydání:	2009
Předmět:	Pulmonary and Respiratory Medicine Lung business.industry medicine.disease Procalcitonin respiratory tract diseases Sepsis Pneumonia medicine.anatomical_structure Immunology medicine Biomarker (medicine) Sputum Exhaled breath condensate medicine.symptom business Asthma
Zdroj:	Pneumologie. 63:439-450
ISSN:	1438-8790 0934-8387
DOI:	10.1055/s-0029-1214799
Popis:	Biological markers in various compartments of the human body have demonstrated potential value in diagnosis, prediction, guidance of therapy as well as in monitoring the clinical course of diseases of the airways and the lung. But only certain surrogate parameters are from clinical value, such as procalcitonin in pneumonia and sepsis, alpha-1-antitrypsin to diagnose alpha-1-antitrypsin deficiency, D-Dimers to detect emboli, nitric oxide in exhaled air in asthma, or isolation of germs from sputum to guide antibiotic treatment. Quantification of numerous markers in exhaled breath condensate or the detection of compounds in exhaled air are more recent attempts to further elucidate those biomarkers for clinical use. In general, biomarkers have an important supportive value in addition to routine diagnostic methods. The article reviews recent data regarding the usefulness of markers in non-malignant pulmonary diseases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ecbfa9d2d9e2fa40a9e48c19d86c7b4d https://doi.org/10.1055/s-0029-1214799 Zobrazit plný text záznamu