Kinetic study of asymmetric hydrogenation of methyl levulinate using the (COD)Ru(2-methylallyl)2–BINAP–HCl catalytic system

Autor:	O. V. Turova, E. V. Starodubtseva, V. A. Ferapontov, Maxim G. Vinogradov
Rok vydání:	2009
Předmět:	Hydride Process Chemistry and Technology Asymmetric hydrogenation Enantioselective synthesis Substrate (chemistry) chemistry.chemical_element Photochemistry Medicinal chemistry Catalysis Ruthenium chemistry.chemical_compound Catalytic cycle chemistry Physical and Theoretical Chemistry BINAP
Zdroj:	Journal of Molecular Catalysis A: Chemical. 311:61-65
ISSN:	1381-1169
DOI:	10.1016/j.molcata.2009.06.024
Popis:	The kinetics of asymmetric hydrogenation of methyl levulinate in the presence of the (COD)Ru(2-methylallyl)2–BINAP–HCl catalytic system was studied. The kinetic order in H2, as well as in the catalyst, was found to be equal to 1, whereas the kinetic order for the substrate and HCl falled from 1 to 0 with their increasing starting concentration. The kinetic and 31P NMR data testify that the mechanism of the reaction under consideration, most likely, involves the hydride transfer to the protonated substrate in the dinuclear ruthenium complex as the rate-limiting step of the catalytic cycle.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ecbc040b75c0c792413e34bc72062edb https://doi.org/10.1016/j.molcata.2009.06.024 Zobrazit plný text záznamu Full Text from ScienceDirect