Antigen-specific factors produced by carrier-primed New Zealand Black mice

Autor:	S Sawada, M J Dauphinée, N Talal
Rok vydání:	1980
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 124:1263-1266
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.124.3.1263
Popis:	We studied antigen-specific suppression in NZB and B/W mice to investigate immunoregulatory circuits associated with autoimmune disease. Young NZB and B/W mice produced ample suppressor factor, and acceptor cells were present even in older mice. A low m.w. antigen-specific enhancing factor capable of augmenting the secondary in vitro IgG antibody response to DNP was found. These results indicate the complexity of immunoregulation in these autoimmune-susceptible mice.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ecaed5117de4abf735ec8fff8c27c0bf https://doi.org/10.4049/jimmunol.124.3.1263 Zobrazit plný text záznamu