Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracrânienne

Autor: T. Faillot, M.-C. Vergnes, B. Lestienne, Jean-François Payen, Nicolas Bruder, C. Bernard, Jean-Luc Bosson, Gérard Audibert
Rok vydání: 2005
Předmět:
Zdroj: Annales Françaises d'Anesthésie et de Réanimation. 24:921-927
ISSN: 0750-7658
Popis: The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor deficit, a meningioma or malignant tumour, a large tumour, age over 60 years, surgery lasting more than 4 hours, a chemotherapy. The benefit of mechanical methods or low molecular weight heparin (LMWH) for the prevention of DVP in neurosurgery is demonstrated (grade A). Each method decreases the risk by about 50%. A postoperative prophylaxis with a LMWH does not seem to increase the risk of intracranial bleeding (grade C). There is no demonstrated benefit to begin a prophylaxis with LMWH before the intervention. The duration of the prophylaxis is 7 to 10 days but this has not been scientifically determined.
Databáze: OpenAIRE