| Autor: |
Hideo Hakusui, Shouzou Shintani, Masayoshi Fujimaki |
| Rok vydání: |
1989 |
| Předmět: |
|
| Zdroj: |
Drug Metabolism and Pharmacokinetics. 4:673-677 |
| ISSN: |
0916-1139 |
| DOI: |
10.2133/dmpk.4.673 |
| Popis: |
Transfer of the radioactivity into the milk was studied after a single oral administration of 14C-carvedilol at a dose of 10 mg/kg to lactating rats. The concentrations of radioactivity in the milk were higher than that in the plasma throughout the experimental period. The disappearance of the radioactivity from the milk was slower than that from the plasma and the milk-to-plasma concentration ratio reached the value of 7.3 at 8h after dosing in lactating rats. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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