Diastereoselective 1,3-dipolar cycloaddition of Sm(III)-azomethine ylides to α,β-unsaturated esters

Autor:	Aurelio G. Csaky, Carlos Alvarez-Ibarra, M. Martínez, M. Luz Quiroga
Rok vydání:	1996
Předmět:	Chemistry Organic Chemistry Drug Discovery 1 3-Dipolar cycloaddition Fragmentation (computing) Biochemistry Medicinal chemistry Cycloaddition
Zdroj:	Tetrahedron Letters. 37:6573-6574
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)01402-5
Popis:	Sm(III)-Azomethine ylides were generated by fragmentation of the iminodithiocarbonates 1 with SmI2 in THF. 1,3-Dipolar cycloaddition of these species with α,β-unsaturated esters 3 afforded the highly functionalized 2-methylthio-Δ1-pyrrolines 4 with good yields and diastereoselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ec9bf3a13ab9838b7124a278dcef1b6b https://doi.org/10.1016/0040-4039(96)01402-5 Zobrazit plný text záznamu Full Text from ScienceDirect