Use of galvanostatic coulometry for determining nitroxoline

Autor: Guzel Ziyatdinova, G. K. Budnikov, O. V. Shlyamina, S. G. Abdullina
Rok vydání: 2007
Předmět:
Zdroj: Journal of Analytical Chemistry. 62:957-959
ISSN: 1608-3199
1061-9348
DOI: 10.1134/s1061934807100103
Popis: It was found that nitroxoline rapidly and quantitatively reacts with electrogenerated chlorine or bromine. The stoichiometric coefficients of these reactions are 1: 1.5 and 1: 1, respectively. The mechanism of the reaction of nitroxoline with electrogenerated bromine was proposed. A procedure was developed for the quantitative determination of nitroxoline in the substance and pharmaceuticals with a relative standard deviation of 1–3%.
Databáze: OpenAIRE