Self-assembled aggregation-induced emission micelle (AIE micelle) as interfacial fluorescence probe for sequential recognition of Cu2+ and ATP in water
| Autor: | Wan Sun, Zhong-Lin Lu, Zheng-Li Tan, You-Di Shi, Lan He, Ai-Xiang Ding, Ke-Xin Zhang |
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| Rok vydání: | 2018 |
| Předmět: |
inorganic chemicals
Detection limit Aqueous solution 010405 organic chemistry Metals and Alloys Analytical chemistry Tetraphenylethylene 010402 general chemistry Condensed Matter Physics Photochemistry 01 natural sciences Fluorescence Micelle 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Ion chemistry.chemical_compound chemistry Amphiphile Materials Chemistry Electrical and Electronic Engineering Instrumentation Stoichiometry |
| Zdroj: | Sensors and Actuators B: Chemical. 255:440-447 |
| ISSN: | 0925-4005 |
| DOI: | 10.1016/j.snb.2017.08.037 |
| Popis: | Cu2+ ions and adenosine-5′-triphosphate (ATP) play important roles in the process of cellular metabolism, building artificial chemosensor for detecting them are of great significance. In this work, on the basis of a tetraphenylethylene (TPE) amphiphile (1) which can generate the aggregation-induced emission (AIE) micelles through self-assembling in aqueous solution, we developed a new interfacial system for sequential recognitions of Cu2+ and ATP with high selectivity and sensitivity. Once Cu2+ was introduced into the 100% aqueous solution of probe 1, a complex composed by the probe and Cu2+ with a 1:2 stoichiometry was formed, leading to remarkable fluorescence quenching. Adding ATP to the solution of the in situ generated 1-Cu2+ ensemble can easily recover the fluorescence of the system. The limits of detection (LoD) for Cu2+ and ATP were calculated to be 1.0 × 10−7 and 1.5 × 10−6 M. Both 1 and the resultant 1-Cu2+ complex were demonstrated to have low cytotoxicity and good cell-membrane permeability, they were successfully applied to image Cu2+ ions and ATP in living HepG2 cells. |
| Databáze: | OpenAIRE |
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