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Globularia alypum (G. alypum) is a medicinal plant commonly used intradi-tional pharmacopoeias. In this study, the antioxidant and anti-inflammatory activities of G. alypum lyophilized aqueous extract were evaluated. Male Wistar rats (n=24) weighing 232±10g were divided into 4 groups (n=6). Two control groups were fed a standard-diet (St-D) supplemented (C-Ga) or not (C) with 1.66% G. alypum extract. The two others were fed enriched choles-terol diet (EC-D) for 15 days, which contains the St-D plus 1% of cholesterol and 0.5% of cholic acid (HC) with the same amount of G. alypum (HC-Ga). At d28, EC-D leads to increase TBARS concentrations in plasma, lipoproteins (VLDL-LDL, HDL), tissues (liver, heart, kidney and adipose tissues) and ery-throcytes (p |
