| Autor: |
Xin Zhu, Xiao Jie Li, Yang Liu, Xi Shan Guo, Yin Fei Zheng |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Materials Science Forum. 1058:99-104 |
| ISSN: |
1662-9752 |
| DOI: |
10.4028/p-8kmke2 |
| Popis: |
This report studies the charge-based sensing modality of FET-embedded nanopore biosensors through FEM simulation. PNP equation is solved to analyze the mirror charge introduced by charged biomolecule while threading through the nanopore-FET sensor. Negative and positive charged molecules are analyzed respectively. Obvious local potential change induced by the presenting of charged molecules nearby is observed. In addition, the transport-induced descreening effect is observed under intensive bias, which might explain the capability of charge sensing even under high concentrations such as 1 M for FET-nanopore biosensors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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