Mixed systems based on aminated and sulfonated silica nanoparticles: synthesis, self-assembly, and selective adsorption of certain biopolymers
| Autor: | Aigul R. Nugmanova, Ivan I. Stoikov, Yu. N. Osin, Vladimir G. Evtugyn, L. S. Yakimova |
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| Rok vydání: | 2019 |
| Předmět: |
biology
010405 organic chemistry Chemistry Nanoparticle General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Adsorption Sulfonate Chemical engineering Selective adsorption biology.protein Surface modification Self-assembly Bovine serum albumin Macromolecule |
| Zdroj: | Russian Chemical Bulletin. 68:262-269 |
| ISSN: | 1573-9171 1066-5285 |
| DOI: | 10.1007/s11172-019-2381-y |
| Popis: | Hybrid aminated and sulfonated nanoparticles were synthesized by surface modification of silica nanopowder with 3-aminopropyltriethoxysilane and 1,3-propanesultone, respectively. The developed protocols for the synthesis of three types of "buffer" mixed submicron particles with corresponding ζ-potentials (–21.4±1.3, 4.7±0.4, 12.4±0.8) were based on various methods of nanoprecipitation of synthesized silica nanoparticles modified by amino- and sulfonate groups, and on various conditions of these precepitation (solvent, temperature). Hybrid SiO2 particles, as well as self-assembling associates based on sulfonated and aminated particles, were examined in extraction of biologically important macromolecules. It was established that the efficiency of adsorption of calf thymus DNA increased with increasing zeta potentials of the modified silica particles studied. The interaction of the studied model proteins (bovine serum albumin and lysozyme) with the synthesized silica nanoparticles modified by sulfonate groups increased as the pH of the medium decreased. |
| Databáze: | OpenAIRE |
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