Targeting Plasmodium Proteases to Block Malaria Parasite Escape and Entry
| Autor: | Manoj T. Duraisingh, Aditya S. Paul |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Proteases Protease medicine.medical_treatment Plasmepsin Biology medicine.disease biology.organism_classification Virology Plasmodium 03 medical and health sciences 030104 developmental biology Infectious Diseases Drug development parasitic diseases medicine Parasite hosting Parasitology Malaria |
| Zdroj: | Trends in Parasitology. 34:95-97 |
| ISSN: | 1471-4922 |
| Popis: | Proliferation of malaria parasites in a host requires mechanisms to spread between red blood cells (RBCs). We discuss here the implications for biology and antimalarial drug development of companion studies that establish the requirement of two Plasmodium spp. proteases of the plasmepsin family in parasite egress from, and invasion into, RBCs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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