ChemInform Abstract: Synthesis of New Fluorescent Nucleoside Analogues and Application to the Study of Human Deoxycytidine Kinase

Autor:	Jean Louis Imbach, Staffan Eriksson, Manijeh Shafiee, Gilles Gosselin, Georges Maury
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Enzyme chemistry Biochemistry Nucleic acid Cytidine General Medicine Deoxycytidine kinase Enantiomer Nucleoside Fluorescence
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199942246
Popis:	We have determined the affinity of human deoxycytidine kinase with respect to new fluorescent N-methylanthraniloyl cytidine derivatives or non fluorescent enantiomeric cytidine analogues. New results regarding the enantioselectivity and the mechanism of the enzyme are presented.
Databáze:	OpenAIRE
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