Comparative Study Between The Clinical Effects of Glucosamine/Gingko Biloba & Glucosamine/Chondroitin in Treatment of Knee Osteoarthritis
| Autor: | Mohammed D. Al-Rekabi |
|---|---|
| Rok vydání: | 2014 |
| Zdroj: | Kufa Journal for Nursing Sciences. 4:102-109 |
| ISSN: | 2521-8638 2223-4055 |
| DOI: | 10.36321/kjns.vi20142.2552 |
| Popis: | Objectives: This study was designed to investigate the effect of two widely used combinations, glucosamine / chondroitin and glucosamine/ginkgo biloba on the clinical picture of patient with osteoarthritis (OA). Methodology: Fifty one (51) osteoarthritis patients (21 male and 30 female) were participated in this researchdepending on certain selection criteria. The selected patient were randomly allocated into two groups: groupA includes 22 (9 male and 13 female) patients treated with a combination of glucosamine /gingko biloba (500/ 50 mg twice daily) for six weeks whereas group B includes 29 (12 male and 17 female) patients treated with a combination of glucosamine/chondroitin (500/ 400mg twice daily ) for six weeks . Effects of drug treatment were assessed each seven days by clinical evaluation and direct interview with patients through a questionnaire method known as Knee Injury and Osteoarthritis Outcome Score (KOOS). Results: It was found that all components of KOOS including pain score, symptoms score, activity of daily living (ADL), quality of life (QOL) and sport & recreation scores were significantly elevated (improved) in both combinations, however, glucosamine /gingko biloba showed a better improvement when statistically compared with the combination of glucosamine/chondroitin. Conclusions: It is concluded of this study that the glucosamine sulfate is more clinically useful for OA when combined with gingko biloba than when it is combined with chondroitin. Recommendations: A large scale cohort study is recommended to ensure the clinical findings. |
| Databáze: | OpenAIRE |
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