Further study of antiinflammatory effects ofAbies pindrow

Autor:	Rakesh K. Singh, B. L. Pandey
Rok vydání:	1997
Předmět:	Pharmacology chemistry.chemical_classification Abies pindrow biology Traditional medicine business.industry fungi Flavonoid Glycoside Arthritis Inflammation biology.organism_classification medicine.disease Terpenoid law.invention chemistry law Edema medicine medicine.symptom business Phytotherapy
Zdroj:	Phytotherapy Research. 11:535-537
ISSN:	1099-1573 0951-418X
DOI:	10.1002/(sici)1099-1573(199711)11:7<535::aid-ptr146>3.0.co;2-f
Popis:	Abies pindrow leaves are used as an Ayurvedic remedy for disorders with inflammatory symptoms. The antiinflammatory effect was established in preliminary studies. Fractional extraction of the leaves indicated uneven predominance of flavonoids, glycosides, terpenoids and steroids. An antiinflammatory effect in the 5 h carrageenin oedema model was exhibited by all fractions, indicating multiple active principles. Studies in granuloma pouch and adjuvant arthritis models in rats also indicated a significant antiinflammatory effect. The polar constituents were more inhibitory to acute, while non-polar ones prominently inhibited the chronic inflammatory reactions. No immunomodulatory effect could be indicated as such. © 1997 John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
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