Prevalence of hepatitis B virus and associated factors among pregnant women in the health facilities, N'djamena, Chad

Autor: Nalda Debsikreo, Birwé Léon Mankréo, Merwa Ouangkake, Madjikoula Jotham, Anna Julienne Selbé Ndiaye, Nafissatou Leye, Gora LO, Azoukalné Moukenet, Ali Mahamat Moussa, Ndèye Coumba Toure-Kane, Françoise Lunel-Fabiani
Rok vydání: 2023
Popis: Background Hepatitis B virus (HBV) infection is a major global health problem. In Chad, the prevalence is estimated at 19% in the overall population. Control hepatitis B among pregnant women may help to break the chain of transmission. However, the prevalence and risk factors of hepatitis B among pregnant women in N'Djamena are not documented. The aim of this study was to establish the HBV prevalence and identify the risk factors associated with hepatitis B in pregnant women in N'Djamena. Methods We conducted a cross-sectional study in eight health facilities in the city of N'Djamena (Chad) from April 4 to August 2, 2021. HBV surface antigen was determined using the SD Bioline HBsAg WB rapid test. We performed a Chi-squared test and an adjusted logistic regression to identify risk factors associated with hepatitis B infection. Results A total of 458 pregnant women were included in the study. The average age of participants was 25 years (95% CI: 20–30). Among risk factors, being older (age > 35 years) and having been tested for HBsAg increase the likelihood of being HBsAg+ (OR = 1.22, 95% CI: 0.33–3.92, p = 0.001, and OR = 4.93, 95% CI: 2.05-12.0, p
Databáze: OpenAIRE