Cytological Evaluation of Tongue Cells and Buccal Mucosa Cells
| Autor: | Ege Gulec Balbay, Cem Şahiner, Feyza Başar, Murat Oktay, Anzel Bahadir, Nilüfer Kadıoğlu, Leyla Yilmaz Aydin, Havva Erdem |
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| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Prognostic factor business.industry Cell Buccal mucosa Pathology and Forensic Medicine Staining stomatognathic diseases medicine.anatomical_structure Tongue medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Surgery Oral Surgery Head and neck business neoplasms |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 119:e139 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2014.07.159 |
| Popis: | Objective: C-erbB-2 expression has been detected in 40 to 60% of head and neck squamous cell carcinomas (HNSCC). With regard to preneoplastic lesions, thus suggesting that the loss of CerbB-2 expression is a carcinogenic molecular event. Study Design: This study was conducted on a total of 20 paraffin-embedded HNSCC samples, which were histopathologically diagnosed at the Department of Pathology of medicine Hospital between 2010 and 2011. Paraffin-embedded HNSCC samples 3 mm in thickness, were then cut. The slides were stained with C-erbB-2. Results: There was significant relationship between staining density and differentiation grade (R1⁄4 0,922671). Conclusions: Consequently, it was concluded that cerbB-2 is a poor prognostic factor in HNSCC like in breast tumour. |
| Databáze: | OpenAIRE |
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