ChemInform Abstract: Accessing Skeletal Diversity Using Catalyst Control: Formation of n and n + 1 Macrocyclic Triazole Rings

Autor:	Sarathy Kesavan, Jean-Charles Marie, Ann Rowley Kelly, Jingqiang Wei, Damian W. Young, Lisa A. Marcaurelle, Nicole Windmon
Rok vydání:	2009
Předmět:	Ring size chemistry.chemical_classification chemistry.chemical_compound chemistry Stereochemistry Intramolecular force Triazole Regioselectivity Alkyne General Medicine Cycloaddition Catalysis
Zdroj:	ChemInform. 40
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200944164
Popis:	A regioselective intramolecular Huisgen cycloaddition was performed on various azido alkyne substrates giving rise to macrocyclic triazole rings. Using catalyst control, a common intermediate has been converted to two structurally unique macrocycles with either a 1,5- or a 1,4-triazole resulting in an n or n + 1 ring size. This is the first example of an intramolecular ruthenium-catalyzed Huisgen cycloaddition.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ebf59d8c07e3bd02ef885d203e07f6e4 https://doi.org/10.1002/chin.200944164 Zobrazit plný text záznamu Plný text