Prostaglandin analogs. 2. 15,15-Ketals of natural prostaglandins and prostaglandin analogs. Synthesis and biological activities

Autor:	Werner Skuballa, Walter Elger, O. Loge, H. Vorbrueggen, B Raduechel
Rok vydání:	1978
Předmět:	chemistry.chemical_compound Prostaglandin analog Biochemistry Chemistry Prostaglandin E2 receptor Drug Discovery Luteolysis Discovery and development of cyclooxygenase 2 inhibitors Molecular Medicine Prostaglandin lipids (amino acids peptides and proteins) Inducer
Zdroj:	Journal of Medicinal Chemistry. 21:443-447
ISSN:	1520-4804 0022-2623
Popis:	The synthesis is described of new 15,15-ethylene ketals of natural prostaglandins and prostaglandin analogues. Especially the crystalline trisamine salt of the 15,15-ethylene ketal of 15-dehydro-16-phenoxy-17,18,19,20-tetranorprostaglandin F2alpha is a very active inducer of luteolysis in laboratory animals and cattle.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ebde16912842f3d94becce0b9c7de77b https://doi.org/10.1021/jm00203a007 Zobrazit plný text záznamu