Myocardial infarction and percent arteriographic stenosis of culprit lesion

Autor: James R. Boen, Henry Buchwald, David W. Hunter, Jack L. Titus, Christian T. Campos, Naip Tuna, Stanley E. Williams, Betty J. Hansen
Rok vydání: 1998
Předmět:
Zdroj: Atherosclerosis. 138:391-401
ISSN: 0021-9150
DOI: 10.1016/s0021-9150(98)00049-5
Popis: The objective of this study was to assess the percent stenosis of the culprit lesion responsible for subsequent myocardial infarction in the Program on the Surgical Control of the Hyperlipidemias (POSCH). It is unknown if the susceptible coronary artery culprit lesion responsible for an acute myocardial infarction is relatively large ( > or = 50% arteriographic stenosis) and hemodynamically significant ( > or = 70% stenosis), or small ( or = 70%. The results strongly favor the large lesion hypothesis of causation for myocardial infarction. It is premature, however, to state that the relative size of the culprit lesion has been indisputably determined. The resolution of this problem has exceedingly important practical implications for the management of patients with known atherosclerotic coronary heart disease and for those asymptomatic individuals with silent atherosclerotic coronary heart disease.
Databáze: OpenAIRE