Epidemiology of anaerobic infections of the female genito-urinary tract, and preliminary results of therapy with erythromycin

Autor: G. Tolkmitt, H. Werner, R. Feddern, N. Lang, C. Kraseman
Rok vydání: 1978
Předmět:
Zdroj: Current Medical Research and Opinion. 5:52-55
ISSN: 1473-4877
0300-7995
DOI: 10.1185/03007997809110252
Popis: SummaryThe frequency of anaerobes with possible clinical significance was studied in healthy pregnant and puerperal women. Only 5% of the 100 healthy pregnant women studied yielded non-sporing anaerobes of the families Bacteroidaceae and Peptococcaceaefrom vaginal swabs. However, the incidence of clinically important anaerobes in 133 puerperal women was 42%. Mixed infections were most frequent. The predominant anaerobic species was Bacteroides oralis. Patients suffering from post-partum endometritis or other infections with local pain and fever were treated with 2 g erythromycin daily for 5 days. The anaerobes isolated were, without exception, sensitive to erythromycin. With therapy, temperature returned to normal within 5 days or less. The beneficial effect of erythromycin therapy, even in mixed infections, may possibly indicate that anaerobes play an important pathogenic role in female genital tract infections.
Databáze: OpenAIRE