Application of [3 + 2]-Cycloaddition in the Synthesis of Valdecoxib

Autor:	Aalla Sampath, Gilla Goverdhan, Rakeshwar Bandichhor, Anumula Raghupathi Reddy, Padi Pratap Reddy, Khagga Mukkanti
Rok vydání:	2011
Předmět:	chemistry.chemical_compound chemistry Nitrile Organic Chemistry medicine Organic chemistry Valdecoxib Cycloaddition medicine.drug Enamine
Zdroj:	Synthetic Communications. 42:639-649
ISSN:	1532-2432 0039-7911
Popis:	A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3 + 2]-dipolar cycloaddition involving enamine and in situ–generated nitrile oxide derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eba49fa8e72d42b159f0170d017940f8 https://doi.org/10.1080/00397911.2010.528572 Zobrazit plný text záznamu