Synthesis of the metabolites of 2-(N-benzyl-N-methylamino)ethyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride (nicardipine hydrochloride, YC-93)

Autor:	Murakami Masuo, Iwanami Masaru, Toichi Takenaka, Fujimoto Masaharu, Tadao Shibanuma
Rok vydání:	1980
Předmět:	chemistry.chemical_classification Chemistry Hydrochloride Dihydropyridine General Chemistry General Medicine chemistry.chemical_compound Drug Discovery Nicardipine Hydrochloride Pyridine medicine Organic chemistry Lactone Catalytic hydrogenation medicine.drug
Zdroj:	Chemical and Pharmaceutical Bulletin. 28:2609-2613
ISSN:	1347-5223 0009-2363
Popis:	Eight metabolites (M-1-M-6, M-8, M-9) of 2-(N-benzyl-N-methylamino)ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hydrochloride (YC-93) were synthesized and the structures of the metabolites were established by comparison with the synthetic compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eb9be71a85e9a6fd06c7ea2af67c07d0 https://doi.org/10.1248/cpb.28.2609 Zobrazit plný text záznamu