Accuracy and Effect Upon Clinical Workload of the MS-2 Urine Screen and Antibiotic Susceptibility System
| Autor: | W. Jeff Hodges, Kenneth C. Godowski |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Pathology
medicine.medical_specialty Veterinary medicine biology medicine.drug_class Detection threshold Gram-positive bacteria Biochemistry (medical) Clinical Biochemistry Antibiotics Liter Bacteriuria Urine biology.organism_classification medicine.disease Decreased Sensitivity medicine Urine screen |
| Zdroj: | Laboratory Medicine. 12:758-764 |
| ISSN: | 1943-7730 0007-5027 |
| DOI: | 10.1093/labmed/12.12.758 |
| Popis: | A total of 794 midstream urine specimens were screened using the Abbott MS-2 system, and the results were compared with those obtained by routine plating methods. Sensitivity of detection of ≥105 colony-forming units per milliliter (CFU/mL) for urinary pathogens was 96.5%; lowering of the detection threshold to ≥104 CFU/ml decreased sensitivity to 93.8%. Specificity was 92.5%. Antibiotic susceptibility tests were performed on 122 freshly isolated gram-negative and grampositive bacteria using the MS-2 system, and the results were compared with those of microdilution MIC methodology. For gram-positive isolates, full accord of results was found in 84.3% and essential accord in 94.8% of isolates tested. For gram-negative isolates, full accord was found in 89.0% and essential accord in 96.0% of isolates tested. Workload studies indicated a technical time savings of 24% with use of the automated MS-2 instrument. |
| Databáze: | OpenAIRE |
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